Supplements: Moducare

Moducare supports both the immune and adrenal system.

For people with Hashimoto’s, too much pressure on the adrenal makes the body wear out faster. This is a letdown since people with Hashimoto’s have to prioritize the condition of their adrenal, whether they suffer from stress or depression.

Thorne Moducare is especially recommended since it moderates both the adrenal and immune system. It modulates Th1 and Th2 helper cells which enhance cellular immunity and responses. It also is incorporated with natural balancers, plants sterols and sterolins. Moducare keeps the adrenal hormone and DHEA ratio in check and also alleviates stress. Even when given in a low dose, moducare improves the activity of cells which in turn is linked to better immune response for people with Hashimoto’s.

Moducare Dosage

This supplement works really well since it is hard to establish how much of it is actually available in vegetables and the food we take. Its effectiveness is influenced by the person, situation and how severe your Hashimoto’s is. Ensure that you try several amounts of this drug, after talking with your medic of course, to know what works best for you. This drug should be taken thrice (variable) on an empty stomach for best results. The right dose is normally known after indulging your GP.

Advantages of Taking Moducare

Moducare is very useful in reducing thyroid antibodies as well as other antibodies related to development of autoimmune reactions. It also improves adrenal functions. Since it reduces the number of immunoglobulin, your immune system is restored and can defend you better. If either the immune system or adrenal is damaged, both can become malfunctioned at the same time. Moducare ensures that both the adrenal and immune system function properly. In a survey that was performed, there was quicker and healthier immune response in patients who were given moducare.

Supplements: Ferritin

In the formation of hair structure, ferritin plays an important role in making it fine. Ferritin is also the protein which takes part in protein storage and its deficiency may cause anemia. Discoveries have been made linking loss of hair to ferritin deficiency in premenopausal women.

Other uses of ferritin is the deployment and use of the T3 hormones in cells. There are more than one way of being deficient of ferritin other than starvation. In women, it is vital to observe the onset of hair loss since it may be an indication of ferritin deficiency.

Doctors recommend that women maintain their ferritin above 12 and 150 ng/ml for hair loss, maintaining it above 40 ng/ml will reverse it, 90-110 ng/ml will ensure your thyroid still functions as normal and finally, 70ng/ml will completely rid yourself of hair loss. Also, women are particularly at risk of ferritin deficiency because of pregnancy and menstruation. Pregnancy may make you lose up to 600-1000 mg of iron while menstruation contributes to 10-15 mg iron loss with each menstrual cycle.

For iron to be effectively absorbed it requires you have normal stomach acid that is hydrochloric acid. If you are medicated acid suppressants, less iron is thus absorbed.

When taking iron supplements such as Opti-Ferrin, you should employ caution since sometimes overdosing it is lethal and tends to be toxic.

The following concerns should be addressed when choosing a supplement:

  • Ensure that the supplement you choose does not contain synthetic extracts. If there are even minimal traces of such they can be severely injurious to health and even interfere with absorption. Synthetic additives of gluten or dairy should not be included in the supplement.
  • Choose B12 supplements containing methyl alcohol simply because they are more effective compared to cyan cobalamin.
  • Folic acid should mirror methyl folate metafolin or natural folate, especially if you have MTRH gene variation.
  • Ensure the supplements are checked for wholesomeness and they have similar contents to the indicated description

Supplements: Magnesium

Magnesium is a nutrient that is usually deficient in patients with thyroid and is responsible for multiple symptoms which can cause severe thyroid anomalies. The following symptoms can be used to determine whether you have magnesium deficiency or not:

  • Prolonged periods of unhappiness
  • Cross and irritable
  • Difficulty maintaining your concentration
  • An autistic spectrum in your family history
  • Restlessness
  • Regular migraines or headaches
  • Family or individual history of diabetes
  • Swallowing difficulty
  • Exhaustion
  • Asthma in the family history
  • Infrequent and hardened bowels
  • Extreme stress
  • Insomnia or trouble staying asleep
  • Jerking of muscles
  • Premenstrual syndrome
  • Cramps on the legs or hands
  • Restless leg syndrome
  • Irregularities in the heart beat
  • Family or individual history of kidney stones
  • Individual or family history of heart complications
  • Individual or family history of mitral valve prolapse
  • Low intake of kelp, almonds, some nuts and seeds, or dark leafy vegetables.
  • Severe joint and menstrual cramps along with leg cramps.

The prevalence of magnesium deficiency

There are two major types of magnesium deficiencies, these are: overt deficiencies which cause low plasma calcium and potassium levels. This type of condition is regarded as severe but is also quite scarce. Subclinical deficiencies will not be detected easily on common blood tests but diagnosis can be done from the above symptoms.

You are at risk of developing magnesium deficiency if:

  • You are an alcoholic
  • Have severe diarrhea
  • People with Crohn’s disease
  • Older adults due to reduced efficiency of the gut
  • People being given medication which can impair magnesium absorption
  • People with hypothyroidism
  • If you suffer from type II diabetes

Sources of magnesium are majorly green leafy vegetables, fortified cereals, grains, legumes and some seeds. Also, following a Paleo diet should ensure that you get high levels of magnesium. Avoid caffeine, stress and toxins since they deplete magnesium.

Magnesium is very important as a laxative and in addressing some of patient symptoms including:

  • Constipation
  • Insomnia
  • Menstrual cramps
  • Body cramps
  • Restlessness
  • Headaches

However, magnesium can delay absorption of thyroid medication. Always take magnesium 4 hours before your thyroid medication intake.

Supplements: Vitamin D

Most people with Hashimoto’s are often diagnosed with vitamin D deficiency. This deficiency is linked to the presence of antibodies which assume the thyroid to be an invader.

Vitamin D plays a vital part in sustaining the immune system, building resistance against infections and keeping your gut in good health. It is important in preventing and controlling autoimmunity and this is essential to people who were previously diagnosed with Epstein-Barr infection, as the cells that kill the virus are dependent on vitamin D. This infection can also trigger Hashimoto’s.Health experts have a reason to suppose that this deficiency is more likely to develop in people living away from the equator since vitamin D is basically found form sunlight.

Sitting under sunlight regularly makes most people feel better. Vitamin D is also involved in enhancing memory, and studies show that regular exposure to sunlight can make Hashimoto’s patients relieve some of the symptoms.

For optimal thyroid reception and normal functioning of the immune system, vitamin D levels should be elevated to between 60-80 ng/L. The most recommended brand of vitamin D supplement is provided by Pure Encapsulations.


The best way to elevate your vitamin D levels is by exposure to sunlight, safe tanning beds and an oral vitamin D3 supplement. You can avoid vitamin D deficiency using your diet by making available foods such assalmon and cod liver oil. Conversely, you need to expose yourself to sunlight if you cannot absorb vitamin rich foods efficiently.

Recommendations have been made that you sit under sunlight at around noon without sunscreen. If you are fair skinned and can’t tolerate it, start by limiting your exposure time and gradually increase it with time. Be careful so that you avoid getting sunburns. With rising cases of vitamin D deficiency, health experts advise that you should increase exposure to sunlight.

Supplement: Vitamin B12

A deficiency of vitamin B12 may lead to one or all of the following: anemia, impaired digestion due to malformation of villi and inflammation. Vitamin B12 is obtained from animal proteins in our diet.

Low Levels of Vitamin B12

There are clinical tests that are employed to determine the levels of this vitamin, but they are not very comprehensive. It has been found that low ranges are too low and normal-low levels are linked to developing neurologic symptoms including memory lapse, mania, difficulty balancing, psychosis and fatigue.

Vitamin B12 is released after digestion by the action of hydrochloric acid and protease enzyme. People with Hashimoto’s have a risk of having B12 deficiency since they have a tendency to be with low stomach acid. Vitamin B12 is fortified in some processed food such as bread and ingestion of such foods can mask the deficiency.

Foods which are naturally rich in vitamin B12 are

  • Fish
  • Poultry
  • Meat
  • Eggs
  • Milk and its products

Vitamin B12 is rarely found in vegetables and other plants, therefore, vegetarians have an increased risk of developing a deficiency of this vitamin. Taking vitamin B12 supplements is helpful for vegetariansespecially those suffering from pernicious anemia and low stomach acid, until the deficiency is healed.

Vitamin B12 supplements can be administered in form of tablets, sublingual (under the tongue) liquids and as an injection. The sublingual route is most favorable with added advantages to it compared to giving injections.

For starters, the initial dose through the sublingual route is 1 mg to 3mg of vitamin B12 for 10 days, and the subsequent doses are given once per week. It has been witnessed that monthly doses are very resourceful in restoring vitamin B12 levels for people who suffered a deficiency.

Pure Encapsulations brand of methylated B12 is advised for most people with Hashimoto’s.

Supplements: Thiamine (Vitamin B1)

Thiamine is involved in the discharge of energy from starch or sugar and also takes part in digestion of proteins and fats. It also helps in releasing the right amount of HCL for digestion. Thiamine promotes blood sugar function, adrenals and boosting energy levels. As known, Hashimoto’s patients have little or no stomach acid hence thiamine is a huge relief.

From conducted studies, it has been revealed that there is thiamine deficiency in people with autoimmune reactions, and it is more severe in alcoholics. Most of the processed foods are fortified with thiamine, but since you will be avoiding such foods chances of developing thiamine deficiency are increased.

Symptoms of thiamine deficiency include:

  • Exhaustion
  • Ill-temper
  • Depression
  • Abdominal distress
  • Low blood pressure
  • Low stomach acid
  • Trouble digesting carbohydrates
  • Brain fog
  • Heart damage in the long run
  • Breathing difficulty

The commonly prescribed dosage of thiamine is 1.1 mg for women. In other countries the dose is as high as 600 mg. For best results when using thiamine, also incorporate benfotiamine in your use. 600 mg as a dose is extremely high and you may have to take multiple capsules to attain that target. Thiamine has been found to ease fatigue in Hashimoto’s patients considerably.

However, there is no clinical test that can be done to prove that you have mild deficiency since it only affirms severe deficiency. However, if you showed some of the above symptoms of thiamine deficiency, visiting your general practitioner soon is advised for checkups.

Supplements which boost the action of thiamine are benfotiamine by Douglas Labs (four per day) or benfomax by Pure Encapsulations (three per day).

Thiamine boosts energy levels and also normalizes blood pressure. In as much as thiamine is effective, it is important you combine it with a Paleo diet to get better results in digestion, energy levels and blood pressure.

Supplements: Systemic Enzymes

Systemic enzymes are natural immune moderators and can lessen thyroid antibodies and relieve many food sensitivities. They also break down immune complexes which are responsible in inducing autoimmune diseases.

What are Systemic Enzymes?

These are plant and animal enzyme derivatives which contain the following ingredients; bromelain, papain, rutin, chymotrypsin, trypsin, pancreatin.

How it is Administered

Systemic enzymes should not be taken with food; on an empty stomach at least 45 minutes before the next meal.

Action of Systemic Enzymes

When the body has an autoimmune reaction, it releases proteolytic enzymes to suppress it. However sometimes the immunity becomes overburdened with circulating immune complexes, and can lead to liver congestion, severe autoimmune diseases and even heart attacks.

In order to reduce circulatory immunity complexes, limit intake of reactive proteins, which impairs liver function causing immunity imbalance. It is also advisable to avoid gluten diets since they also are triggers.

Systemic enzymes are also effective and reduce immunoglobulin to food and thyroid reducing circulatory immunity complexes which induce autoimmune responses. Also, systemic enzymes disintegrate inflammatory cytokines which are present during autoimmune reactions, and have proteases that can be used in phagocytizing pathogens. They can also accelerate tissue repair after inflammation.

General tissue health can be supported by systemic enzymes as well as reinforcing the immune system.

Advantages of Using Systemic Enzymes

By taking systemic enzymes, the appearance of the thyroid as well as elimination of antibodies from the thyroid is witnessed. TSH and antibodies are also normalized and also their general health is improved. This supplement is very effective when taken with a healthy diet. There is also tremendous reduction of food allergies in most of the patients.

The dose of systemic enzymes may be varied depending on how severe your condition is and also your general health.

To patients ravaged with Hashimoto’s, this supplement was found to be very helpful as a majority of them healed completely. The thyroid was effective in getting rid of antibodies and food sensitivities were reduced.

Supplements: Betaine With Pepsin

This supplement supports stomach acid and thyroid disorders.

Hashimoto’s and Low Stomach Acid

Betaine with pepsin has been found to be effective against excessive fatigue. Sometimes, after taking betaine with pepsin, you wake up hours earlier than expected having surplus of time to budget for.

Most of the people affected with Hashimoto’s are diagnosed with low stomach acid. This condition consequently leads to slower digestion of food provoking food allergies, which irritate and burden the immune system.

If you have Hashimoto’s then it is more likely you also have inadequate or no stomach acid. This can make you susceptible to:

  • Parasitic infections from undigested food.
  • Develop severe food allergies
  • Infestation of the small intestines with excess bacteria
  • Depletion of nutrients (calcium, ferratin etc.)
  • If this condition is left untreated, you may develop hypergastrinemia and hazardous cancers.

Achlorhydria and Hypochlordria Symptoms

There are very minimal symptoms of low stomach acid. The most pronounced one is feeling exhausted and full after meals, and sometimes resemble acid reflux signs. This acid reflux-like symptoms, by giving antacids may actually worsen.

Betaine HCl and Pepsin

Betaine and pepsin are incorporated within gastric juice naturally, to aid in making amino acids and nutrients easily absorbed after digestion. Betaine HCL is used in promoting gastric lumen acidity whereaspepsin is an enzyme used to digest proteins.

Betaine HCL With Pepsin

There was positive feedback after administering this drug. Taking betaine and pepsin has the following advantages:

  • Less energy is used during digestion
  • Amino acids are made more available for absorption
  • You develop less food allergies or none
  • Food is digested faster and you don’t crave for more.

Since most Hashimoto’s patients have low stomach acid, this drug is efficient in improving it.

People Who Should Not Use Betaine With Pepsin:

  • Those taking medication which can cause ulcers
  • People using a proton pump inhibitor medication

Proper Dosing

Capsules should be increased by one, after every meal, until you develop high acid level symptoms. At this point, one dose less in recommended.

Taking apple cider vinegar or lemon juice can also elevate stomach acid.


Supplements: Selenium

Selenium is a natural remedy which delays oxidation of polyunsaturated fatty acids and maintains tissue elasticity. Selenium is an ingredient in secretion of prostaglandins, which assist in blood flow. They also work with vitamin E to improve fertility, healthy growth and functions of certain cells in creating energy. Selenium also supports the immune system and improves the natural defenses of the body. Having a deficiency of selenium may induce Hashimoto’s.

Hashimoto’s in conjunction with selenium deficiency is linked to severe gastrointestinal complications.  Selenium deficiency may be caused by disorders of an inflamed bowel and celiac disease.

Selenium is important in controlling the amount of hydrogen peroxide in the body, preventing an autoimmune response. Hydrogen peroxide damages cells if left to accumulate to high levels. Selenium forms selenoproteins to safeguard the body from the damage due to hydrogen peroxide, and conversion of T4 into active T3.

Recommended Selenium Dosage

It is recommended that you take 200 mcg to assist in lessening the number of thyroid antibodies by half in six months. There is a positive response that is gotten if the right dosage of selenium is taken. In the USA, 55-400 mcg is the recommended dosage. Since people are different, some symptoms may manifest in other people which are symptoms of selenium toxicity, including:

  • Changes in hair and nails
  • Hair loss
  • Extreme exhaustion
  • Irritability
  • Peripheral neuropathy
  • Garlic-smelling breath
  • Yellowing of the skin and eyes

Selenium toxicity is mainly due to mishaps in manufacturing of apparatus.

The level of selenium in soil or farm produce is greatly varied with the geographical location. However, the full potential of selenium is achieved based on the ability to digest foods with it.

The dose should be formulated after indulging the doctor and can thereafter be moderated to fit individual needs

Advantages of Taking selenium

Selenium helps to

  • Reduce damage to tissues
  • Improving thyroid conversion and lessening anxiety minimizing destruction to thyroid tissues.

Supplements: Probiotics

Probiotics are recommended for people with Hashimoto’s. Probiotics helps in eliminating harmful bacteria in the gut, relieving symptoms of intestinal permeability. Other than this, there are some other causes of intestinal permeability.

Gluten also induces intestinal permeability. Studies show that discontinuing gluten intake can treat autoimmune responses.

The gut can also be permeable if the number of essential bacteria are overshadowed by harmful bacteria (opportunistic pathogens). The only unwanted effect that antibiotics have is that in as much as they eliminate injurious bacteria, they also kill useful bacteria.

There is a test called Gastrointestinal Function Comprehensive Profile – Genova kit which assesses the number of bacteria on the gut. Eating fermented foods and probiotics promotes growth of beneficial bacteria in the gut which may help in case of Hashimoto’s.

How to Administer Probiotics

Always ensure you get the dosage right. Start with a low dose and then progressively increase the dose. Consult the local GP to test what is best suited for you. Probiotics are available in several forms but it is advised you take them in supplement form if possible.

The best probiotics in the market are MegaSporeBiotic, VSL#3, Pure Encapsulations, Probiotic 50B, and Klaire Labs Ther biotic among others.

Note that Probiotic 50B, VSL#3, and Klaire Ther-Biotic all must be refrigerated and used at room temperature so that bacteria remain feasible for a period of two weeks.

Benefits of Taking Probiotics

The main benefit of probiotics is that they help in digestion and extraction of nutrients from ingested food thus sustaining the immune system. Also, they do help in relieving some of the gut symptoms including small intestinal bacterial overgrowth (SIBO), which is more evident in a majority of Hashimoto’s patients( more than 50%), and can also cause leaky gut. Probiotics also treat anxiety and encourage breakdown of food. Probiotic supplements are best taken on an empty stomach so that they are taken into the blood stream much faster.